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Our customer service representatives are available 24 hours, Monday through Friday to assist you.| Introduction | Urokinase (UK) is a serine protease, which is one of biological plasminogen activators. It is involved in a number of biological functions including fibrinolysis, embryogenesis, cell migration, tissue remodeling, ovulation, and wound healing. It can be obtained from human urine or kidney cell culture. |
| Synonyms | Urokinase, Abbokinase, Urokinase-type Plasminogen Activator,uPA, EC 3.4.21.73, UK. |
| Source | Human urine. |
| Physical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. |
| Formulation | The Urokinase was lyophilized from a concentrated (1mg/ml) solution containing phosphate buffer. |
| Solubility | It is recommended to reconstitute the lyophilized Urokinase in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. |
| Stability | Lyophilized Urokinase althoµgh stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Urokinase should be stored at 4°C between 2-7 days and for future use below -18°C.Please prevent freeze-thaw cycles. |
| Purity | Greater than 92.0% as determined by SDS-PAGE. |
| Usage | NeoBiolab's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals. |
| References | 1. Title:Transient ?-catenin stabilization modifies lineage output from human thymic CD34+CD1a– progenitors. Publication:Published online before print December 1, 2009, doi: 10.1189/jlb.0509344 March 2010 Journal of Leukocyte Biology vol. 87 no. 3 405-414 .Link:http://www.jleukbio.org/content/87/3/405.full2.Title:Activation of human pro-urokinase by unrelated proteases secreted by Pseudomonas aerµginosa.Publication:Received 26 November 2009/18 March 2010; accepted 2Link:http://www.biochemj.org/bj/428/0473/bj4280473.htm |
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