YWHAH Human-14-3-3

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YWHAH Human

Qty


Total
$65
Catalog #
PKPS-354
Size
Description
YWHAH Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 266 amino acids and having a molecular mass of 30.3 kDa. YWHAH is fused to N-Terminus His Tag and purified by proprietary chromatographic techniques.
Additional Information
IntroductionYWHAH belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. 14-3-3 ETA is found in plants and mammals, and there is 99% identity to the mouse, rat and bovine orthologs. YWHAH gene contains a 7 base pair repeat sequence in its 5' UTR, and changes in the number of this repeat has been associated with early-onset schizophrenia.14-3-3 eta is specific to the site of joint inflammation. 14-3-3 proteins are colocalized with Lewy bodies in Parkinson disease, thoµgh there is no specific staining for the 14-3-3 eta subunit. There are 3 different isoforms types of 14-3-3: Beta, Gamma and ETA that are DAL-1/Protein 4.1B-binding proteins.
Synonyms14-3-3 ETA, YWHAH, YWHA1, Protein AS1, Tyr-3/Trp-5 Monooxygenase Activation Protein ETA.
SourceEscherichia Coli.
Physical AppearanceSterile filtered colorless solution.
FormulationYWHAH solution containing 20mM Tris pH-8.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MGDREQLLQR
ARLAEQAERY
DDMASAMKAV
TELNEPLSNE
DRNLLSVAYK
NVVGARRSSW
RVISSIEQKT
MADGNEKKLE
KVKAYREKIE
KELETVCNDV
LSLLDKFLIK
NCNDFQYESK
VFYLKMKGDY
YRYLAEVASG
EKKNSVVEAS
EAAYKEAFEI
SKEQMQPTHP
IRLGLALNFS
VFYYEIQNAP
EQACLLAKQA
FDDAIAELDT
LN
PurityGreater than 95.0% as determined by SDS-PAGE.
UsageNeoBiolab's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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