YARS Human-Synthetase

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YARS Human

Qty


Total
$65
Catalog #
ENPS-141
Size
Description
YARS produced in E.Coli is a single, non-glycosylated polypeptide chain containing 548 amino acids (1-528 a.a.) and having a molecular mass of 61.3kDa.YARS is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Additional Information
IntroductionTyrosyl-tRNA synthetase (YARS) is a member of the class I tRNA synthetase family. YARS is a vital enzyme which catalyzes the aminoacylation of tRNATrp with tryptophan, a critical function of the cell’s protein synthesis machinery. Expression of YARS is highly stimulated in human cells by the addition of IFN-gamma.
SynonymsTyrosyl-tRNA synthetase cytoplasmic, Tyrosyl--tRNA ligase, TyrRS, YARS, YRS, YTS, CMTDIC.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered colorless solution.
FormulationYARS protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 10% glycerol and 0.1M NaCl.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MGDAPSPEEK
LHLITRNLQE
VLGEEKLKEI
LKERELKIYW
GTATTGKPHV
AYFVPMSKIA
DFLKAGCEVT
ILFADLHAYL
DNMKAPWELL
ELRVSYYENV
IKAMLESIGV
PLEKLKFIKG
TDYQLSKEYT
LDVYRLSSVV
TQHDSKKAGA
EVVKQVEHPL
LSGLLYPGLQ
ALDEEYLKVD
AQFGGIDQRK
IFTFAEKYLP
ALGYSKRVHL
MN
PurityGreater than 90.0% as determined by SDS-PAGE.
UsageNeoBiolab's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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