WARS Human-Synthetase

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WARS Human

Qty


Total
$65
Catalog #
ENPS-552
Size
Description
WARS Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 491 amino acids (1-471 a.a.) and having a molecular mass of 55.3 kDa. The WARS is fused to 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
Additional Information
IntroductionWARS is part of the class I tRNA synthetase family. 2 types of tryptophanyl tRNA synthetase exist, a cytoplasmic form, called WARS, and a mitochondrial form, called WARS2. WARS catalyzes the aminoacylation of tRNA(trp) with tryptophan and is induced by interferon. WARS controls ERK, Akt, and eNOS activation pathways that are related with angiogenesis, cytoskeletal reorganization and shear stress-responsive gene expression.
SynonymsGAMMA-2, IFI53, IFP53, WRS, WARS, TrpRS, hWRS, EC=6.1.1.2, Tryptophanyl-tRNA synthetase, Interferon-induced protein 53, Tryptophan--tRNA ligase, GAMMA-2.
SourceEscherichia Coli.
Physical AppearanceSterile filtered colorless solution.
Formulation1mg/ml solution containing 20mM Tris-HCl pH-8, 1mM DTT, 0.1M NaCl, 1mM DTT & 10% glycerol.
StabilityWARS Human althoµgh stable at 4°C for 1 week, should be stored desiccated below -18°C. Please prevent freeze thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MPNSEPASLL
ELFNSIATQG
ELVRSLKAGN
ASKDEIDSAV
KMLVSLKMSY
KAAAGEDYKA
DCPPGNPAPT
SNHGPDATEA
EEDFVDPWTV
QTSSAKGIDY
DKLIVRFGSS
KIDKELINRI
ERATGQRPHH
FLRRGIFFSH
RDMNQVLDAY
ENKKPFYLYT
GRGPSSEAMH
VGHLIPFIFT
KWLQDVFNVP
LVIQMTDDEK
YLWKDLTLDQ
AY
PurityGreater than 90.0% as determined by SDS-PAGE.
UsageNeoBiolab's products are furnished forLABORATORY RESEARCHUSEONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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