VAPB Human-Synaptobrevin

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VAPB Human

Qty


Total
$65
Catalog #
PRPS-021
Size
Description
VAPB Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 242 amino acids (1-222 a.a.) and having a molecular mass of 27.1kDa. The VAPB is purified by proprietary chromatographic techniques.
Additional Information
IntroductionVAPB Vesicle-associated membrane protein (VAMP)-associated protein B (aka VAPB) is a type IV transmembrane protein and belongs to the VAP family of proteins. VAPB may have a role in vesicle trafficking. VAPB is found in plasma and intracellular vesicle membranes as a homodimer and heterodimer with VAPA, and interacts with VAMP1 and VAMP2. VAPB defects are the basis for the amyotrophic lateral sclerosis type 8 and spinal muscular atrophy autosomal dominant Finkel type.
SynonymsVesicle-associated membrane protein-associated protein B/C, VAMP-B/VAMP-C, VAMP-associated protein B/C, VAP-B/VAP-C, VAPB, ALS8, VAP-B, VAMP-B.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered colorless solution.
FormulationThe VAPB solution (1 mg/ml) contains 20mM Tris-HCl buffer (pH8.0) and 10% glycerol.
StabilityVAPB should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MAKVEQVLSL
EPQHELKFRG
PFTDVVTTNL
KLGNPTDRNV
CFKVKTTAPR
RYCVRPNSGI
IDAGASINVS
VMLQPFDYDP
NEKSKHKFMV
QSMFAPTDTS
DMEAVWKEAK
PEDLMDSKLR
CVFELPAEND
KPHDVEINKI
ISTTASKTET
PIVSKSLSSS
LDDTEVKKVM
EECKRLQGEV
QRLREENKQF
KEEDGLRMRK
TVQSNSPISA
LA
PurityGreater than 90.0% as determined by SDS-PAGE.
UsageNeoBiolab's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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