SIRT2 Human-Sirtuin

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SIRT2 Human

Qty


Total
$65
Catalog #
PRPS-040
Size
Description
SIRT2 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 372 amino acids (1-352a.a.) and having a molecular mass of 41.7kDa.SIRT2 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Additional Information
IntroductionSIRT2 belongs to the sirtuin family of proteins, homologs to the yeast Sir2 protein. Proteins of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes and take part in various processes, including transcriptional regulation, cell cycle progression, DNA-damage repair and aging. SIRT2 is a NAD-dependent deacetylase, which deacetylates the 'Lys-40' of alpha-tubulin.
SynonymsSirtuin 2, SIR2L2, SIR2-like protein 2, NAD-dependent deacetylase sirtuin-2, Silent Information Regulator 2.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered clear solution.
FormulationThe SIRT2 protein solution (0.25mg/1ml) is formulated in 20mM Tris-HCl buffer (pH8.0) 2mM DTT, 200mM NaCl, 0.5mM EDTA and 30% glycerol.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MDFLRNLFSQ
TLSLGSQKER
LLDELTLEGV
ARYMQSERCR
RVICLVGAGI
STSAGIPDFR
SPSTGLYDNL
EKYHLPYPEA
IFEISYFKKH
PEPFFALAKE
LYPGQFKPTI
CHYFMRLLKD
KGLLLRCYTQ
NIDTLERIAG
LEQEDLVEAH
GTFYTSHCVS
ASCRHEYPLS
WMKEKIFSEV
TPKCEDCQSL
VKPDIVFFGE
SLPARFFSCM
QS
PurityGreater than 90% as determined by SDS-PAGE.
UsageNeoBiolab's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
StorageStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.Please avoid freeze thaw cycles.
Background

N/A

Protocol

N/A

MSDS
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