PTPS Human-Synthase

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PTPS Human

Qty


Total
$65
Catalog #
ENPS-478
Size
Description
6-PyruvoylTetrahydropterin Synthase Human Recombinant produced in e.coli is a single, non-glycosylated polypeptide chain containing 165 amino acids (1-145) and having a molecular mass of 18.5kDa. 6-PyruvoylTetrahydropterin Synthase is fused to a 20 amino acid His Tag at N-terminus and purified using conventional chromatography techniques.
Additional Information
Introduction6-PyruvoylTetrahydropterin Synthase is part of the family of lyases, specifically those carbon-oxygen lyases acting on phosphates. 6-PyruvoylTetrahydropterin Synthasecatalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin, is a necessary cofactor and regulator of a range of enzyme activities, including enzymes involved in serotonin biosynthesis and NO synthase activity. Mutations in 6-PyruvoylTetrahydropterin Synthase gene result in hyperphenylalaninemia.
SynonymsPTP Synthase, 6-Pyruvoyl Tetrahydropterin Synthase, PTPS, PTS, FLJ97081.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered colorless solution.
Formulation6-PyruvoylTetrahydropterin Synthase is formulated in 20mM Tris-HCl buffer pH-8, 1mM DTT and 20% glycerol.
Stability6-PyruvoylTetrahydropterin Synthase althoµgh stable 4°C for 4 weeks, should be stored desiccated below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MSTEGGGRRC
QAQVSRRISF
SASHRLYSKF
LSDEENLKLF
GKCNNPNGHG
HNYKVVVTVH
GEIDPATGMV
MNLADLKKYM
EEAIMQPLDH
KNLDMDVPYF
ADVVSTTENV
AVYIWDNLQK
VLPVGVLYKV
KVYETDNNIV
VYKGE.
PurityGreater than 95.0% as determined by Analysis by SDS-PAGE.
UsageNeoBiolab's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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