PSMF1 Human-Proteasome

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PSMF1 Human

Qty


Total
$65
Catalog #
ENPS-231
Size
Description
PSMF1 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 291 amino acids (1-271) and having a molecular mass of 31.9kDa.PSMF1 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Additional Information
IntroductionPSMF1 is a protein which hinders the activation of the proteasome by the 11S and 19S regulators. The 26S proteasome is a multicatalytic proteinase complex with an extremely ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is comprised of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits.
SynonymsProteasome inhibitor PI31 subunit, hPI31, PSMF1, PI31.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered colorless solution.
FormulationThe PSMF1 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 20% glycerol, 1mM DTT and 0.1mM PMSF.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MAGLEVLFAS
AAPAITCRQD
ALVCFLHWEV
VTHGYCGLGV
GDQPGPNDKK
SELLPAGWNN
NKDLYVLRYE
YKDGSRKLLV
KAITVESSMI
LNVLEYGSQQ
VADLTLNLDD
YIDAEHLGDF
HRTYKNSEEL
RSRIVSGIIT
PIHEQWEKAN
VSSPHREFPP
ATAREVDPLR
IPPHHPHTSR
QPPWCDPLGP
FVVGGEDLDP
FGPRRGGMIV
DP
PurityGreater than 85.0% as determined by SDS-PAGE.
UsageNeoBiolab's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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