PSME1 Human-Proteasome

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PSME1 Human

Qty


Total
$65
Catalog #
PRPS-273
Size
Description
PSME1 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 269 amino acids (1-249a.a.) and having a molecular mass of 30.8kDa.PSME1 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Additional Information
IntroductionPSME1 is an interferon gamma (IFNG) inducible proteasome activator essential for presentation of certain major histocompatibility (MHC) class I antigens. The PSME1 complex is an alternate proteasome activator which operates with no use of ubiquitin. The PSME1 complex is made out of two homologous subunits, alpha and beta, that functions in similar catalytic properties and is connected to a hexameric ring.
SynonymsREG-alpha, PA28alpha, PA28a, Proteasome Activator subunit-1, Proteasome Activator 28 subunit alpha, Interferon gamma up-regulated I-5111 protein.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered clear solution.
FormulationThe PSME1 protein solution (0.5mg/1ml) is formulated in 20mM Tris-HCl buffer (pH8.0) 0.1M NaCl and 10% glycerol.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MAMLRVQPEA
QAKVDVFRED
LCTKTENLLG
SYFPKKISEL
DAFLKEPALN
EANLSNLKAP
LDIPVPDPVK
EKEKEERKKQ
QEKEDKDEKK
KGEDEDKGPP
CGPVNCNEKI
VVLLQRLKPE
IKDVIEQLNL
VTTWLQLQIP
RIEDGNNFGV
AVQEKVFELM
TSLHTKLEGF
HTQISKYFSE
RGDAVTKAAK
QPHVGDYRQL
VHELDEAEYR
DI
PurityGreater than 90% as determined by SDS-PAGE.
UsageNeoBiolabs products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
StorageStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.Please avoid freeze thaw cycles.
Background

N/A

Protocol

N/A

MSDS
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