PSMB7 Human-Proteasome

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PSMB7 Human

Qty


Total
$65
Catalog #
ENPS-584
Size
Description
PSMB7 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 255 amino acids (44-277) and having a molecular mass of 27.6kDa (Molecular size on SDS-PAGE will appear higher).PSMB7 is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Additional Information
IntroductionProteasome subunit beta type-7 (PSMB7) belongs to the proteasome B-type family. PSMB7 is a multicatalytic proteinase complex with an extremely ordered ring-shaped 20S core structure. This core structure is comprised of 4 rings of 28 non-identical subunits; 2 rings are comprised of 7 alpha subunits and 2 rings are comprised of 7 beta subunits. Proteasomes are scattered all over eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent manner in a non-lysosomal pathway. The processing of class I MHC peptides is a vital function of the immunoproteasome (which is a modified proteasome).
SynonymsProteasome subunit beta type-7, Macropain chain Z, Multicatalytic endopeptidase complex chain Z, Proteasome subunit Z, PSMB7, Z.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered colorless solution.
FormulationThe PSMB7 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 20% glycerol and 1mM DTT.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MTTIAGVVYK
DGIVLGADTR
ATEGMVVADK
NCSKIHFISP
NIYCCGAGTA
ADTDMTTQLI
SSNLELHSLS
TGRLPRVVTA
NRMLKQMLFR
YQGYIGAALV
LGGVDVTGPH
LYSIYPHGST
DKLPYVTMGS
GSLAAMAVFE
DKFRPDMEEE
EAKNLVSEAI
AAGIFNDLGS
GSNIDLCVIS
KNKLDFLRPY
TVPNKKGTRL
GRYRCEKGTT
AV
PurityGreater than 80.0% as determined by SDS-PAGE.
UsageNeoBiolab's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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