PRDX5 Human-Peroxiredoxin

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PRDX5 Human

Qty


Total
$65
Catalog #
ENPS-433
Size
Description
PRDX5 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 162 amino acids (53-214 a.a.) and having a molecular mass of 17 kDa.The PRDX5 is purified by proprietary chromatographic techniques.
Additional Information
IntroductionPRDX5 belongs to the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides with reducing equivalents supplied throµgh the thioredoxin system. PRDX5 has an antioxidant protective function in different tissues under normal conditions and during inflammatory processes. Peroxiredoxin-5 interacts with peroxisome receptor 1 and is involved in intracellular redox signaling. PRDX5 is involved in intracellular redox signaling. Peroxiredoxin-5 is a significant antioxidant protein of lung epithelial cells for its expression in the human lung increases during inflammation. PRDX5 expression is upregulated in osteoarthritis. PRDX5 may be significant in mitochondrial genome stability. Peroxiredoxin-5 has a protective role in human tendon cells against oxidative stress by reducing apoptosis and upholding collagen synthesis.
SynonymsPeroxiredoxin-5 mitochondrial, Prx-V, Peroxisomal antioxidant enzyme, Thioredoxin reductase, Thioredoxin peroxidase PMP20, Antioxidant enzyme B166, TPx type VI, Liver tissue 2D-page spot 71B, Alu corepressor 1, PLP, ACR1, B166, PRXV, PMP20, PRDX6, SBBI10,
SourceEscherichia Coli.
Physical AppearanceSterile Filtered colorless solution.
FormulationThe PRDX5 solution contains 20mM HEPES buffer (pH 7.4).
StabilityPRDX5 althoµgh stable 4°C for 4 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Amino Acid SequenceMAPIKVGDAI
PAVEVFEGEP
GNKVNLAELF
KGKKGVLFGV
PGAFTPGCSK
THLPGFVEQA
EALKAKGVQV
VACLSVNDAF
VTGEWGRAHK
AEGKVRLLAD
PTGAFGKETD
LLLDDSLVSI
FGNRRLKRFS
MVVQDGIVKA
LNVEPDGTGL
TCSLAPNIIS
QL.
PurityGreater than 95.0% as determined by SDS-PAGE.
Biological ActivityThe specific activity was found to be approximately 117-136 pmole/min/
UsageNeoBiolab's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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