PRDX3 Human-Peroxiredoxin

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PRDX3 Human

Qty


Total
$65
Catalog #
ENPS-426
Size
Description
PRDX3 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 195 amino acids (63-256 a.a.) and having a molecular mass of 21.5 kDa.The PRDX3 is purified by proprietary chromatographic techniques.
Additional Information
IntroductionPRDX3 is part of the peroxiredoxin family of antioxidant enzymes, that reduces hydrogen peroxide and alkyl hydroperoxides. PRDX3 is particularly located in the mitochondria and involved in the regulation of cellular redox status by serving as a primary line of defense against H2O2 produced during respiration. PRDX3 is a significant regulator of the abundance of mitochondrial H(2)O(2), which itself promotes apoptosis in cooperation with other mediators of apoptotic signaling. PRDX3 mitochondrial protein is significantly decreased in Alzheimer Disease and Down Syndrome.
SynonymsAOP1, MER5, AOP-1, SP-22, PRO1748, MGC24293, MGC104387, PRDX3, Thioredoxin-dependent peroxide reductase mitochondrial, Peroxiredoxin-3, PRX III, Antioxidant protein 1, Protein MER5 homolog, HBC189.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered colorless solution.
FormulationThe PRDX3 solution contains 20mM Tris-HCl pH-8, & 10% glycerol.
StabilityPRDX3 althoµgh stable 4°C for 4 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Amino Acid SequenceMPAVTQHAPY
FKGTAVVNGE
FKDLSLDDFK
GKYLVLFFYP
LDFTFVCPTE
IVAFSDKANE
FHDVNCEVVA
VSVDSHFSHL
AWINTPRKNG
GLGHMNIALL
SDLTKQISRD
YGVLLEGSGL
ALRGLFIIDP
NGVIKHLSVN
DLPVGRSVEE
TLRLVKAFQY
VETHGEVCPA
NWTPDSPTIK
PSPAASKEYF
QKVNQ.
PurityGreater than 95.0% as determined by SDS-PAGE.
Biological ActivityThe specific activity was found to be approximately 82-83 pmole/min/
UsageNeoBiolab's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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