PPIL1 Human-Cyclophilin

our services
our products
Quotations & Ordering:

For quotations, please use our online quotation form, and you may also contact us by

service@kendallscientific.com

Phone:

+1-888.733.6849 (Toll-free)
+1-617.299.7367 (Int’l))

Fax:

+1-888.733.6849

Our customer service representatives are available 24 hours, Monday through Friday to assist you.

PPIL1 Human

Qty


Total
$65
Catalog #
ENPS-395
Size
Description
PPIL1 Human Recombinant protein produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 174 amino acids (1-166) and having a molecular mass of 19.3 kDa. PPIL1 is fused to 8 amino acid His Tag at C-terminus and is purified by proprietary chromatographic techniques.
Additional Information
IntroductionPPIL1 belongs to the cyclophilin family of peptidylprolyl isomerases (PPIases). The cyclophilins are a well conserved, ubiquitous family, members of which take an significant part in protein folding, immunosuppression by cyclosporin A, and infection of HIV-1 virions. PPIL1 protein increases the folding of proteins and catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIL1 is involved in proliferation of cancer cells throµgh modulation of phosphorylation of stathmin. PPIL1 is a novel molecular target for colon-cancer therapy.
SynonymsPeptidyl-Prolyl Cis-Trans Isomerase-Like 1, PPIL-1, CYPL1, hCyPX, MGC678, PPIase, CGI-124, PPIL1.
SourceEscherichia Coli.
Physical AppearanceSterile filtered colorless solution.
FormulationPPIL1 solution containing 20 mM Tris-HCl buffer (pH 8.0) and 20% glycerol
StabilityPPIL1 Human Recombinant althoµgh stable at 4°C for 1 week, should be stored desiccated below -18°C. Please prevent freeze thaw cycles.
Amino Acid SequenceMAAIPPDSWQ
PPNVYLETSM
GIIVLELYWK
HAPKTCKNFA
ELARRGYYNG
TKFHRIIKDF
MIQGGDPTGT
GRGGASIYGK
QFEDELHPDL
KFTGAGILAM
ANAGPDTNGS
QFFVTLAPTQ
WLDGKHTIFG
RVCQGIGMVN
RVGMVETNSQ
DRPVDDVKII
KAYPSGLEHH
HHHH.
PurityGreater than 95.0% as determined by SDS-PAGE.
Biological ActivitySpecific activity is > 300 nmoles/min/mg, and is defined as the amount of enzyme that cleaves 1umole of suc-AAFP-pNA per minute at 25C in Tris-Hcl pH8.0 using chymotrypsin.
UsageNeoBiolab's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
Reviews
Kendall Scientific welcomes feedback from its customers.

If you have used an our product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information.

If you have any additional inquiries please email technical services at info@kendallscientific.com.

Thank you for your support.

promotions

Image

Custom Monoclonal Antibody
MassAb Technologies
Image
Free Trial Custom Polyclonal Antibody
You will receive free purified antibodies for validation
Image
Custom Peptides Synthesis

Start from $40/each

new technologies

Image
Optimized for enhanced
expression levels
XPromoter 2.0
Image
E.coli/insect cells/293 & CHO

3 in 1 expression system
Image
MassAb Technologies

Cover All Epitopes