PFN2 Human-Profilin

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PFN2 Human

Qty


Total
$65
Catalog #
PRPS-816
Size
Description
PFN2 Human Recombinant produced in E.Coli is a single, non-glycosylated,polypeptide chain containing 160 amino acids(1-140 a.a.) and having a molecular mass of 17.2 kDa. PFN2 protein is fused to a 20 amino acid His-Tag at N-terminus and purified by standard chromatography.
Additional Information
IntroductionPFN2 is a ubiquitous actin monomer-binding protein which is part of the profilin family. PFN2 regulates actin polymerization in response to extra cellular signals. PFN2 binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, while it increases it at low concentrations. PFN2 binds to PIP2, it inhibits the formation of IP3 and DG.
SynonymsProfilin-II, PFN2, Profilin-2, PFL, D3S1319E.
SourceEscherichia Coli.
Physical AppearanceSterile filtered colorless solution.
FormulationPFN2 protein solution (1mg/ml) containing 20mM Tris-HCl pH-8, 1mM DTT and 10% glycerol.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MAGWQSYVDN
LMCDGCCQEA
AIVGYCDAKY
VWAATAGGVF
QSITPIEIDM
IVGKDREGFF
TNGLALGAKK
CSVIRDSLYV
DGDCTMDIRT
KSQGGEPTYN
VAVGRAGRVL
VFVMGKEGVH
GGGLNKKAYS
MAKYLRDSGF.
PurityGreater than 95% as determined by SDS-PAGE.
UsageNeoBiolab's products are furnished forLABORATORY RESEARCHUSEONLY. They may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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