PFDN1 Human-Prefoldin

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PFDN1 Human

Qty


Total
$65
Catalog #
PRPS-284
Size
Description
PFDN1 Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 130 amino acids (14-122 a.a.) and having a molecular mass of 15kDa. The PFDN1 is purified by proprietary chromatographic techniques.
Additional Information
IntroductionPFDN1 is one of 6 subunits of prefoldin, which is a heterohexameric chaperone protein that assists in the proper folding of other proteins. The PFDN1 protein delivers nonnative target proteins, primarily actins and tubulins, to the eukaryotic cytosolic chaperonin for facilitated folding. Defects in PFDN1 presented phenotypes typical of defects in cytoskeletal function, including manifestations of ciliary dyskinesia, neuronal loss, and defects in B and T cell development and function.
SynonymsPrefoldin subunit 1, PFDN1, PFD1, PDF.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered colorless solution.
FormulationThe PFDN1 solution (0.5 mg/ml) contains 20mM Tris-HCl Buffer (pH 8.0) and 20% Glycerol.
StabilityPFDN1 should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MTELQAKVID
TQQKVKLADI
QIEQLNRTKK
HAHLTDTEIM
TLVDETNMYE
GVGRMFILQS
KEAIHSQLLE
KQKIAEEKIK
ELEQKKSYLE
RSVKEAEDNI
REMLMARRAQ.
PurityGreater than 90.0% as determined by SDS-PAGE.
UsageNeoBiolab's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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