PAPSS1 Human-Synthase

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PAPSS1 Human

Qty


Total
$65
Catalog #
ENPS-243
Size
Description
PAPSS1 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 626 amino acids (24-624) and having a molecular mass of 70.9kDa.PAPSS1 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Additional Information
IntroductionPAPSS1 is a bifunctional enzyme with APS kinase and ATP sulfurylase activity. PAPSS1 facilitates two stages in the sulfate activation pathway, yielding 3'-phosphoadenylylsulfate (PAPS). Additionally, PAPSS1 takes part in the biosynthesis of sulfated L-selectin ligands in endothelial cells.
Synonyms3'-phosphoadenosine 5'-phosphosulfate synthase 1, ATPSK1, PAPSS 1, SK 1, 3-prime-phosphoadenosine 5-prime-phosphosulfate synthase 1, bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1, PAPS synthase 1, Sulfurylase kinase 1, EC 2.7.1.25.
SourceE.coli.
Physical AppearanceSterile Filtered colorless solution.
FormulationThe PAPSS1 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 100mM NaCl and 20% glycerol.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MGSHMRATNV
TYQAHHVSRN
KRGQVVGTRG
GFRGCTVWLT
GLSGAGKTTV
SMALEEYLVC
HGIPCYTLDG
DNIRQGLNKN
LGFSPEDREE
NVRRIAEVAK
LFADAGLVCI
TSFISPYTQD
RNNARQIHEG
ASLPFFEVFV
DAPLHVCEQR
DVKGLYKKAR
AGEIKGFTGI
DSEYEKPEAP
ELVLKTDSCD
VNDCVQQVVE
LLQERDIVPV
DA
PurityGreater than 85% as determined by SDS-PAGE.
UsageNeoBiolab's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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