MUTM E.Coli-Glycosylase

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MUTM E.Coli

Qty


Total
$65
Catalog #
ENPS-596
Size
Description
MUTM Recombinant produced in E. coli is a single polypeptide chain containing 289 amino acids (1-269) and having a molecular mass of 32.4kDa.MUTM is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Additional Information
IntroductionMUTM is a base excision repair enzyme that identifies and eliminates a large variety of oxidized purines from correspondingly impaired DNA. MUTM is nondismissable and essential to remove quickly its substrate lesions on the chromosome. MUTM, additionally, mends a large number of the lesions recognized by Endo III, signifying that MUTM takes a prominent part in the overall repair of both purine damage and pyrimidine damage in vivo.
SynonymsFormamidopyrimidine-DNA glycosylase, FPG.
SourceE.coli.
Physical AppearanceSterile Filtered colorless solution.
FormulationThe MUTM solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 100mM Nacl, 1mM DTT and 20% glycerol.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MPELPEVETS
RRGIEPHLVG
ATILHAVVRN
GRLRWPVSEE
IYRLSDQPVL
SVQRRAKYLL
LELPEGWIII
HLGMSGSLRI
LPEELPPEKH
DHVDLVMSNG
KVLRYTDPRR
FGAWLWTKEL
EGHNVLTHLG
PEPLSDDFNG
EYLHQKCAKK
KTAIKPWLMD
NKLVVGVGNI
YASESLFAAG
IHPDRLASSL
SLAECELLAR
VIKAVLLRSI
EQ
PurityGreater than 90% as determined by SDS-PAGE.
UsageNeoBiolab's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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