MAPT Human 381a.a.-Microtubule-Associated Protein

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MAPT Human 381a.a.

Qty


Total
$65
Catalog #
PRPS-049
Size
Description
MAPT Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 401 amino acids (1-381 a.a.) and having a molecular mass of 41.8kDa. The NCBI Accession No. is EAW93573.1.The MAPT is purified by proprietary chromatographic techniques.
Additional Information
IntroductionMicrotubule-associated protein tau (MAPT or Tau) is a protein that stabilizes microtubules. MAPT is abundant in neurons in the central nervous system and is less common elsewhere. When MAPT is defective, and no longer stabilizes microtubules properly, it can result in dementias, such as Alzheimer's disease.
SynonymsMicrotubule-associated protein tau, isoform CRA_f, Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau, MAPT, MAPTL, MTBT1, TAU, MSTD, PPND, DDPAC, MTBT2, FTDP-17, FLJ31424, MGC138549.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered colorless solution.
FormulationThe MAPT solution (0.5 mg/ml) contains 20mM Tris-HCl Buffer (pH 7.5), 1mM DTT and 20% Glycerol.
StabilityMAPT should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MAEPRQEFEV
MEDHAGTYGL
GDRKDQGGYT
MHQDQEGDTD
AGLKESPLQT
PTEDGSEEPG
SETSDAKSTP
TAEAEEAGIG
DTPSLEDEAA
GHVTQARMVS
KSKDGTGSDD
KKAKGADGKT
KIATPRGAAP
PGQKGQANAT
RIPAKTPPAP
KTPPSSGEPP
KSGDRSGYSS
PGSPGTPGSR
SRTPSLPTPP
TREPKKVAVV
RTPPKSPSSA
KS
PurityGreater than 85.0% as determined by SDS-PAGE.
UsageNeoBiolab's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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