IMPA2 Human-Phosphatase

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IMPA2 Human

Qty


Total
$65
Catalog #
ENPS-077
Size
Description
IMPA2 Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 308 amino acids (1-288 a.a.) and having a molecular mass of 33.5kDa. The IMPA2 is purified by proprietary chromatographic techniques.
Additional Information
IntroductionIMPA2 is a member of the inositol monophosphatase family. IMPA2 catalyzes the dephosphoylration of inositol monophosphate and has a significant role in phosphatidylinositol signaling. IMPA2 can use the myo-inositol monophosphates, scylloinositol 1,4-diphosphate, glucose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. IMPA2 is a pharmacological target for lithium Li(+) action in brain. IMPA2 is considered to have a role in schizophrenia and bipolar disorder.
SynonymsInositol monophosphatase 2, IMP 2, IMPase 2, Inositol-1(or 4)-monophosphatase 2, Myo-inositol monophosphatase A2, IMPA2, IMP.18P.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered colorless solution.
FormulationThe IMPA2 solution (0.25 mg/ml) contains 20mM Tris-HCl buffer(pH 8.0), 10% glycerol and 2mM DTT.
StabilityIMPA2 should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MKPSGEDQAA
LAAGPWEECF
QAAVQLALRA
GQIIRKALTE
EKRVSTKTSA
ADLVTETDHL
VEDLIISELR
ERFPSHRFIA
EEAAASGAKC
VLTHSPTWII
DPIDGTCNFV
HRFPTVAVSI
GFAVRQELEF
GVIYHCTEER
LYTGRRGRGA
FCNGQRLRVS
GETDLSKALV
LTEIGPKRDP
ATLKLFLSNM
ERLLHAKAHG
VRVIGSSTLA
LC
PurityGreater than 95.0% as determined by SDS-PAGE.
UsageNeoBiolab's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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