IL 11 Mouse-Interleukin

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IL 11 Mouse

Qty


Total
$65
Catalog #
CYPS-653
Size
Description
Interleukin-11 Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 179 amino acids and having a molecular mass of 19.2kDa. The Mouse IL-11 is purified by proprietary chromatographic techniques.
Additional Information
IntroductionIL11 is a member of the gp130 family of cytokines. These cytokines drive the assembly of multisubunit receptor complexes, all of which contain at least one molecule of the transmembrane signaling receptor IL6ST (gp130). IL-11 is shown to stimulate the T-cell-dependent development of immunoglobulin-producing B cells. It is also found to support the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells.
SynonymsAGIF, Adipogenesis inhibitory factor, Oprelvekin, IL-11, Interleukin-11, Il11.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered White lyophilized (freeze-dried) powder.
FormulationThe protein was lyophilized from a concentrated (1mg/ml) solution with no additives.
SolubilityIt is recommended to reconstitute the lyophilized Interleukin 11 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
StabilityLyophilized Interleukin-11 althoµgh stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IL11 should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Amino Acid SequenceMPGPPAGSPR
VSSDPRADLD
SAVLLTRSLL
ADTRQLAAQM
RDKFPADGDH
SLDSLPTLAM
SAGTLGSLQL
PGVLTRLRVD
LMSYLRHVQW
LRRAGGPSLK
TLEPELGALQ
ARLERLLRRL
QLLMSRLALP
QAAPDQPVIP
LGPPASAWGS
IRAAHAILGG
LHLTLDWAVR
GLLLLKTRL.
PurityGreater than 95.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
Biological ActivityThe ED50 as determined by the dose-dependant stimulation of the proliferation of mouse 7TD1 was found to be less then 1.5 ng/ml, corresponding to a specific activity of 666666.66IU/mg.
UsageNeoBiolab's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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