HPGD Human-Dehydrogenase

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HPGD Human

Qty


Total
$65
Catalog #
ENPS-571
Size
Description
HPGD Recombinant E.coli produced in E.Coli is a single, non-glycosylated polypeptide chain containing 286 amino acids (1-266a.a.) and having a molecular mass of 31.1 kDa. HPGD is fused to 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
Additional Information
IntroductionHPGD is the essential enzyme of prostaglandin degradation. 15-PGDH protein strongly decreases the biologic activity of these molecules by catalyzing the oxidation of the 15-hydroxyl group of prostaglandins to a keto group. GDH1 is involved in numerous physiologic and cellular processes, for instance inflammation.
SynonymsGDH1, SDR36C1, 15-PGDH, PGDH, Prostaglandin dehydrogenase 1,hydroxyprostaglandin dehydrogenase 15-(NAD)
SourceEscherichia Coli.
Physical AppearanceSterile filtered colorless solution.
FormulationThe HPGD protein solution (0.5mg/1ml) is formulated in 20mM Tris-HCl buffer (pH8.0) 0.1M NaCl,1mM DTT and 20% glycerol.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MHVNGKVALV
TGAAQGIGRA
FAEALLLKGA
KVALVDWNLE
AGVQCKAALD
EQFEPQKTLF
IQCDVADQQQ
LRDTFRKVVD
HFGRLDILVN
NAGVNNEKNW
EKTLQINLVS
VISGTYLGLD
YMSKQNGGEG
GIIINMSSLA
GLMPVAQQPV
YCASKHGIVG
FTRSAALAAN
LMNSGVRLNA
ICPGFVNTAI
LESIEKEENM
GQYIEYKDHI
KD
PurityGreater than 95% as determined by SDS-PAGE.
UsageNeoBiolabs products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
StorageStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.Please avoid freeze thaw cycles.
Background

N/A

Protocol

N/A

MSDS
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