HCV Core Genotype-3/10-Hepatitis C

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HCV Core Genotype-3/10

Qty


Total
$195
Catalog #
HCPS-208
Size
Description
The E.coli derived recombinant protein contains the HCV core nucleocapsid immunodominant regions, amino acids 2-119.
Additional Information
IntroductionHCV is a small 50nm, enveloped, single-stranded, positive sense RNAvirus in the family Flaviviridae. HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host's immune response. Hepatitis C virus is classified into six genotypes(1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6).
SynonymsNULL
SourceNULL
Formulation50mM Tris-HCl, pH-8, 60mM NaCl, 10mM glutathione, 0.25% sarkosil & 50% glycerol.
PurityHCV Core Genotype-3/10 protein is >95% pure as determined by 10% PAGE (coomassie staining).
UsageNeoBiolab's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
ApplicationsHCV Core Genotype-3/10 antigen is suitable for ELISA and Western blots, excellent antigen for detection of HCV with minimal specificity problems.
StorageHCV Core Genotype-3/10 althoµgh stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles.
Purification MethodHCV Core Genotype-3/10 protein was purified by proprietary chromatographic technique.
SpecificityImmunoreactive with sera of HCV-infected individuals.
Background

N/A

Protocol

N/A

MSDS
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