GLUL Human-Synthetase

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GLUL Human

Qty


Total
$65
Catalog #
ENPS-551
Size
Description
GLUL Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 393 amino acids (1-373 a.a.) and having a molecular mass of 44.2 kDa. The GLUL is fused to 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
Additional Information
IntroductionGLUL catalyzes the synthesis of glutamine from glutamate and ammonia. Glutamine is a major source of energy and that takes part in cell proliferation, inhibition of apoptosis, and cell signaling. GLUL is expressed during early fetal stages, and has a role in maintaining body pH by removing ammonia from circulation. Mutations in GLUL gene are related with congenital glutamine deficiency.
SynonymsGLNS, EC 6.3.1.2, EC 4.1.1.15, GLUL, Glutamine Synthetase, GS, Glutamate decarboxylase, Glutamate--ammonia ligase, PIG43, PIG59.
SourceEscherichia Coli.
Physical AppearanceSterile filtered colorless solution.
FormulationGLUL Human solution containing 20mM Tris-HCl pH-8, 5mM DTT, 0.2M NaCl & 20% glycerol.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MTTSASSHLN
KGIKQVYMSL
PQGEKVQAMY
IWIDGTGEGL
RCKTRTLDSE
PKCVEELPEW
NFDGSSTLQS
EGSNSDMYLV
PAAMFRDPFR
KDPNKLVLCE
VFKYNRRPAE
TNLRHTCKRI
MDMVSNQHPW
FGMEQEYTLM
GTDGHPFGWP
SNGFPGPQGP
YYCGVGADRA
YGRDIVEAHY
RACLYAGVKI
AGTNAEVMPA
QWEFQIGPCE
GI
PurityGreater than 90.0% as determined by SDS-PAGE.
UsageNeoBiolab's products are furnished forLABORATORY RESEARCHUSEONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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