FGFR1OP Human-FGF Receptors

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FGFR1OP Human

Qty


Total
$65
Catalog #
PKPS-038
Size
Description
FGFR1OP Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 403 amino acids (1-379 a.a) and having a molecular mass of 43.5kDa.FGFR1OP is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Additional Information
IntroductionFGFR1 oncogene partner (FGFR1OP) is a member of the FGFR1OP family. The FGFR1OP protein is an essentially hydrophilic protein proposed to be a leucine-rich protein family member. A t(6;8)(q27;p11) chromosomal translocation, fusing the FGFR1OP gene and the FGFR1 gene, is seen in cases of myeloproliferative disorder. The ensuing chimeric protein contains the N-terminal leucine-rich region of the FGFR1OP protein fused to the catalytic domain of FGFR1. The FGFR1OP gene is believed to play a significant role in normal proliferation and differentiation of the erythroid lineage.
SynonymsFGFR1 oncogene partner, FGFR1OP, FOP.
SourceEscherichia Coli.
Physical AppearanceSterile filtered colorless solution.
FormulationFGFR1OP protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 10% glycerol and 1mM DTT.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MGSHMAATAA
AVVAEEDTEL
RDLLVQTLEN
SGVLNRIKAE
LRAAVFLALE
EQEKVENKTP
LVNESLKKFL
NTKDGRLVAS
LVAEFLQFFN
LDFTLAVFQP
ETSTLQGLEG
RENLARDLGI
IEAEGTVGGP
LLLEVIRRCQ
QKEKGPTTGE
GALDLSDVHS
PPKSPEGKTS
AQTTPSKKAN
DEANQSDTSV
SLSEPKSKSS
LHLLSHETKI
GS
PurityGreater than 85.0% as determined by SDS-PAGE.
UsageNeoBiolab's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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