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Our customer service representatives are available 24 hours, Monday through Friday to assist you.Introduction | Human Fatty Epidermal Acid Binding Protein FABP also called FABP-5 is a 15 kD member of the intracellular fatty acid binding protein (FABP) family, which is known for the ability to bind fatty acids and related compounds ( bile acids or retinoids). In an internal cavity. The fatty acid binding proteins aP2 (fatty acid binding protein [FABP]-4) and mal1 (EFABP) are closely related and both are expressed in adipocytes. Absence of EFABP/mal1 resulted in increased systemic insulin sensitivity in two models of obesity and insulin resistance. Adipocytes isolated from mal1-deficient mice also exhibited enhanced insulin-stimulated glucose transport capacity. In contrast, mice expressing high levels of mal1 in adipose tissue display reduced systematic insulin activity. |
Synonyms | Fatty acid-binding protein epidermal, E-FABP, Fatty acid-binding protein 5, Psoriasis-associated fatty acid-binding protein homolog, PA-FABP, FABP5, EFABP, PAFABP. |
Source | Escherichia Coli. |
Physical Appearance | Sterile Filtered lyophilized (freeze-dried) powder. |
Formulation | Sterile filtered and lyophilized from 0.5 mg/ml in phosphate buffered saline. |
Solubility | Add 0.2 ml of dH20 and let the lyophilized pellet dissolve completely. |
Stability | Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid freeze-thaw cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C. |
Purity | Greater than 90% as determined by SDS PAGE. |
Usage | NeoBiolab's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals. |
Purification Method | Two-step procedure using size exclusion chromatography before and after refolding. |
Specificity | The amino acid sequence of the recombinant human FABP5 is 100% homologous to the amino acid sequence of the human FABP-5. |
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