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Our customer service representatives are available 24 hours, Monday through Friday to assist you.| Introduction | Neuron-specificNeuron Specific Enolase also caled NSE is a glycolytic isoenzyme which is situated in central and peripheral neurons and neuroendocrine cells. Neuron Specific Enolase-2 is released into the CSF when neural tissue is injured. Neoplasms derived from neural or neuroendocrine tissue release Neuron Specific Enolase-2 into the blood. Neuron Specific Enolase-2 is a useful substance that has been detected in patients with certain tumors, such as neuroblastoma, small cell lung cancer, medullary thyroid cancer, carcinoid tumors, pancreatic endocrine tumors, and melanoma. ENO2 is 1 of the 3 Neuron Specific Enolase isoenzymes found in mammals. ENO2 isoenzyme, is found in mature neurons and cells of neuronal origin. An exchange from alpha Neuron Specific Enolase to gamma Neuron Specific Enolase occurs in neural tissue during development in rats and primates. |
| Synonyms | Gamma-Neuron Specific Enolase, EC 4.2.1.11, 2-phospho-D-glycerate hydro-lyase, Neural Neuron Specific Enolase, Neuron-specific Neuron Specific Enolase, NSE, Neuron Specific Enolase 2, ENO2. |
| Source | Human CNS. |
| Physical Appearance | Sterile Filtered clear solution. |
| Formulation | The protein solution is in 0.01M NaH2PO4 buffer pH 7.4 containing 0.15M NaCl and 0.005M MgSO4. |
| Stability | Human NSE althoµgh stable at 4°C for 1 week, should be stored at -15°C. |
| Purity | Greater than 96.0%. |
| Usage | NeoBiolab's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals. |
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