DUSP21 Human-Phosphatase

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DUSP21 Human

Qty


Total
$65
Catalog #
ENPS-246
Size
Description
DUSP21 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 214 amino acids (1-190) and having a molecular mass of 24.1kDa.DUSP21 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Additional Information
IntroductionDUSP21 is a member of the protein-tyrosine phosphatase family. DUSPs inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residuesb. DUSP21 is able to dephosphorylate single and diphosphorylated synthetic MAPK peptides, favoring the phosphotyrosine and diphosphorylated forms over phosphothreonine. DUSP21 is only expressed in testis where there are dephosphorylated phosphotyrosine residues in MAPK peptides.
SynonymsDual specificity phosphatase 21, Low molecular weight dual specificity phosphatase 21, LMW-DSP21, BJ-HCC-26 tumor antigen, EC 3.1.3.16, EC 3.1.3.48.
SourceE.coli.
Physical AppearanceSterile Filtered colorless solution.
FormulationThe DUSP21 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 200mM NaCl, 2mM DTT and 20% glycerol.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MGSHMTASAS
SFSSSQGVQQ
PSIYSFSQIT
RSLFLSNGVA
ANDKLLLSSN
RITAIVNASV
EVVNVFFEGI
QYIKVPVTDA
RDSRLYDFFD
PIADLIHTID
MRQGRTLLHC
MAGVSRSASL
CLAYLMKYHS
MSLLDAHTWT
KSRRPIIRPN
NGFWEQLINY
EFKLFNNNTV
RMINSPVGNI
PDIYEKDLRM
MISM
PurityGreater than 90% as determined by SDS-PAGE.
UsageNeoBiolab's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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