DUSP19 Human-Phosphatase

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DUSP19 Human

Qty


Total
$65
Catalog #
ENPS-208
Size
Description
DUSP19 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 176 amino acids (65-217) and having a molecular mass of 19.4kDa.DUSP19 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Additional Information
IntroductionDUSPs are distinguished by their ability to dephosphorylate both tyrosine and serine/threonine residues. DUSPs have been implicated as major modulators of critical signaling pathways. Dual specificity phosphatase 19 (DUSP19) belongs to the dual specificity protein phosphatase subfamily. DUSP19 is a protein phosphatase which functions as a stress-activated protein kinase pathway-regulating phosphatase. DUSP19 contains a variation of the consensus DUSP C-terminal catalytic domain, with the last serine residue replaced by alanine, and lacks the N-terminal CH2 domain found in the MKP class of DUSPs.
SynonymsDual specificity protein phosphatase 19, Dual specificity phosphatase TS-DSP1, Low molecular weight dual specificity phosphatase 3, LMW-DSP3, Protein phosphatase, SKRP1, Stress-activated protein kinase pathway-regulating phosphatase 1, SAPK pathway-regula
SourceEscherichia Coli.
Physical AppearanceSterile Filtered colorless solution.
FormulationThe DUSP19 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 30% glycerol and 0.1M NaCl.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MGSQVGVIKP
WLLLGSQDAA
HDLDTLKKNK
VTHILNVAYG
VENAFLSDFT
YKSISILDLP
ETNILSYFPE
CFEFIEEAKR
KDGVVLVHCN
AGVSRAAAIV
IGFLMNSEQT
SFTSAFSLVK
NARPSICPNS
GFMEQLRTYQ
EGKESNKCDR
IQENSS.
PurityGreater than 90.0% as determined by SDS-PAGE.
UsageNeoBiolab's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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