DLD Human-Dehydrogenase

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DLD Human

Qty


Total
$65
Catalog #
ENPS-509
Size
Description
DLD Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 511 amino acids (36-509 a.a.) and having a molecular mass of 54.4 kDa. The DLD is fused to a 37 amino acid His Tag at N-terminus andpurified by proprietary chromatographic techniques.
Additional Information
IntroductionDLD is an L protein of the mitochondrial glycine cleavage system which is also a component of the pyruvate dehydrogenase complex, the alpha-ketoglutarate dehydrogenase complex, and the branched-chain alpha-keto acide dehydrogenase complex. DLD mutations were found in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency.
SynonymsEC 1.8.1.4, DLD, DLDH, GCSL, PHE3, Dihydrolipoyl dehydrogenase mitochondrial, Dihydrolipoamide dehydrogenase, Glycine cleavage system L protein, LAD, E3.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered clear colorless solution.
FormulationThe DLD solution contains 20mM Tris-HCl pH-8, 1mM DTT, 0.1M NaCl and 10% glycerol.
StabilityDLD Recombinant Human althoµgh stable at 4°C for 30 days, should be stored below -20°C for periods greater than 30 days. Please avoid freeze-thaw cycles.
Amino Acid SequenceMRGSHHHHHH
GMASMTGGQQ
MGRDLYDDDD
KDRWGSMADQ
PIDADVTVIG
SGPGGYVAAI
KAAQLGFKTV
CIEKNETLGG
TCLNVGCIPS
KALLNNSHYY
HMAHGKDFAS
RGIEMSEVRL
NLDKMMEQKS
TAVKALTGGI
AHLFKQNKVV
HVNGYGKITG
KNQVTATKAD
GGTQVIDTKN
ILIATGSEVT
PFPGITIDED
TIVSSTGALS
LKKVPEKMVV
IGAGVIGVEL
GS
PurityGreater than 95% as determined by SDS-PAGE.
UsageNeoBiolab's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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