DDAH1 Human-Hydrolase

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DDAH1 Human

Qty


Total
$65
Catalog #
ENPS-021
Size
Description
DDAH1 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 308 amino acids (1-285a.a.) and having a molecular mass of 33.5kDa.DDAH1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Additional Information
IntroductionDimethylarginine dimethylaminohydrolase 1, is a part of the Dimethylarginine Dimethylaminohydrolase gene family. DDAH1 participates in nitric oxide generation by regulating cellular concentrations of methylarginines, that in turn inhibit nitric oxide synthase activity. Deficiency of DDAH1 results inADMA (asymmetric dimethylarginine) increase and a decrease in cGMP generation.
SynonymsDDAH, DDAH-1, Dimethylargininase-1, dimethylargininase-1, Dimethylarginine Dimethylaminohydrolase 1.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered clear solution.
FormulationThe DDAH1 protein solution (1mg/1ml) is formulated in 20mM Tris-HCl buffer (pH 8.0) 1mM DTT, 50mM NaCl and 10% glycerol.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MGSMAGLGHP
AAFGRATHAV
VRALPESLGQ
HALRSAKGEE
VDVARAERQH
QLYVGVLGSK
LGLQVVELPA
DESLPDCVFV
EDVAVVCEET
ALITRPGAPS
RRKEVDMMKE
ALEKLQLNIV
EMKDENATLD
GGDVLFTGRE
FFVGLSKRTN
QRGAEILADT
FKDYAVSTVP
VADGLHLKSF
CSMAGPNLIA
IGSSESAQKA
LKIMQQMSDH
RY
PurityGreater than 95% as determined by SDS-PAGE.
UsageNeoBiolabs products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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