DCPS Human-Other

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DCPS Human

Qty


Total
$65
Catalog #
ENPS-166
Size
Description
DCPS Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 357 amino acids (1-337 a.a.) and having a molecular mass of 40.8kDa.DCPS is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Additional Information
IntroductionScavenger mRNA-decapping enzyme (DCPS) is a member of the HIT family. DCPS is required for the complete degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. It was shown that DCPS hydrolyzes the residual m7GpppN cap structure after the complete 3'–5' degradation of the mRNA by the exosome. Furthermore, DCPS releases m7GMP and is incapable of cleaving cap structures attached to a long RNA chain.
SynonymsScavenger mRNA-decapping enzyme DcpS, DCS-1, Hint-related 7meGMP-directed hydrolase, Histidine triad protein member 5, HINT-5, DCPS, DCS1, HINT5, HSPC015, HSL1.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered clear solution.
FormulationDCPS protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 20% glycerol and 1mM DTT.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MADAAPQLGK
RKRELDVEEA
HAASTEEKEA
GVGNGTCAPV
RLPFSGFRLQ
KVLRESARDK
IIFLHGKVNE
ASGDGDGEDA
VVILEKTPFQ
VEQVAQLLTG
SPELQLQFSN
DIYSTYHLFP
PRQLNDVKTT
VVYPATEKHL
QKYLRQDLRL
IRETGDDYRN
ITLPHLESQS
LSIQWVYNIL
DKKAEADRIV
FENPDPSDGF
VLIPDLKWNQ
QQ
PurityGreater than 90% as determined by SDS-PAGE.
UsageNeoBiolabs products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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