CRYGS Human-Crystallin

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CRYGS Human

Qty


Total
$65
Catalog #
PRPS-970
Size
Description
CRYGS Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 202 amino acids (1-178) and having a molecular mass of 23.6 kDa.The CRYGS is fused to a 24 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
Additional Information
IntroductionMammalian crystallins which are water soluble structural proteins located in the vertebrate eye are classified in three forms, labeled alpha, beta and gamma. Crystallins, the primary components of the lens, raise the refractive index of the eye all throµgh the accommodation by creating high-molecular weight aggregates that maintain transparency. CRYGS is a monomer that does not aggregate. CRYGS encodes the most substantial gamma-crystallin in adult eye lens tissue. Gamma-crystallins has a part in cataract formation due to aging or mutations in specific genes,
SynonymsCrystallin gamma S, Gamma-crystallin S, CRYG8, crystallin, gamma 8, Beta-crystallin S.
SourceE.coli.
Physical AppearanceSterile Filtered colorless solution.
FormulationThe CRYGS solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0) and 10% glycerol.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MGSHMSKTGT
KITFYEDKNF
QGRRYDCDCD
CADFHTYLSR
CNSIKVEGGT
WAVYERPNFA
GYMYILPQGE
YPEYQRWMGL
NDRLSSCRAV
HLPSGGQYKI
QIFEKGDFSG
QMYETTEDCP
SIMEQFHMRE
IHSCKVLEGV
WIFYELPNYR
GRQYLLDKKE
YRKPIDWGAA
SPAVQSFRRI
VE
PurityGreater than 95% as determined by SDS-PAGE.
UsageNeoBiolab's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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