CKMT1 Human-Creatin Kinases

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CKMT1 Human

Qty


Total
$65
Catalog #
CKPS-278
Size
Description
CKMT1 Human Recombinant without C-terminal Lysine on both chains produced in Pichia Pastoris is a glycosylated 47kDa polypeptide chain having an identical amino acid sequence compared to the native enzyme, purified under non-denaturing conditions and reacts with polyclonal antibodies to MM Isoenzyme in ELISA. The CKMT1 is purified by proprietary chromatographic techniques.
Additional Information
IntroductionCreatine Kinase MM is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family.
SynonymsCreatine kinase M-type, EC 2.7.3.2, Creatine kinase M chain, M-CK, CKM, CKMM, CKMMITI.
SourcePichia Pastoris.
Physical AppearanceSterile Filtered colourless liquid formulation.
FormulationCKMT1 contains 0.01M Tris-HCl, 0.075M NaCl, 10mM beta-mercaptoethanol, 50% glycerol, 0.1% sodium azide, pH 7.2.
StabilityCKMT1 althoµgh stable at 15°C for 7 days, should be stored below -18°C. Please prevent freeze-thaw cycles.
PurityGreater than 95.0% as determined bya) Analysis by RP-HPLCb) Analysis by SDS-PAGE
Biological ActivityThe biological activity measured by the enzymatic activity of Creatine phosphokinase procedure No.45-UV, 1IU-1
UsageNeoBiolab's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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