C8G Human-Complement Component

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C8G Human

Qty


Total
$65
Catalog #
PRPS-954
Size
Description
C8G Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 203 amino acids (21-202) and having a molecular mass of 22.6 kDa.The C8G is fused to a 21 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
Additional Information
IntroductionC8, a component of the complement system consists of three polypeptides C8A, C8B and C8G and takes part in the formation of Membrane Attack Complex (MAC). Patients with C8 deficiency are exposed to several bacteria infections. C8G, a member of the lipocalin family and calycin superfamily, is a secreted protein that can bind retinol. C8G is created in the liver, monocytes and fibroblast and has a role in clearing pathogens from an infected host.
SynonymsComplement component 8 gamma polypeptide, C8C, complement component C8 gamma chain, MGC142186.
SourceE.coli.
Physical AppearanceSterile Filtered colorless solution.
FormulationThe C8G solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 2mM DTT, 0.15M NaCl and 10% glycerol.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MQKPQRPRRP
ASPISTIQPK
ANFDAQQFAG
TWLLVAVGSA
CRFLQEQGHR
AEATTLHVAP
QGTAMAVSTF
RKLDGICWQV
RQLYGDTGVL
GRFLLQARGA
RGAVHVVVAE
TDYQSFAVLY
LERAGQLSVK
LYARSLPVSD
SVLSGFEQRV
QEAHLTEDQI
FYFPKYGFCE
AADQFHVLDE
VRR
PurityGreater than 95% as determined by SDS-PAGE.
UsageNeoBiolab's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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