C-JUN Human (241 a.a.)-Jun Proto-Oncogene

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C-JUN Human (241 a.a.)

Qty


Total
$65
Catalog #
PKPS-008
Size
Description
C-JUN Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 261 amino acids (1-241 a.a.) and having a molecular mass of 27.3kDa. The C-JUN is purified by proprietary chromatographic techniques.
Additional Information
IntroductionC-JUN is a gene which, in combination with c-Fos, forms the AP-1early response transcription factor. C-JUN is activated by the JNKpathway. C-JUN is the putative transforming gene of avian sarcoma virus 17. C-JUN is a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. The C-JUN gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies.
SynonymsTranscription factor AP-1, Activator protein 1, AP1, Proto-oncogene c-jun, V-jun avian sarcoma virus 17 oncogene homolog, p39, c-Jun.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered colorless solution.
FormulationThe C-JUN solution (0.25 mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 10% glycerol, 2mM DTT and 0.1M NaCl.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MTAKMETTFY
DDALNASFLP
SESGPYGYSN
PKILKQSMTL
NLADPVGSLK
PHLRAKNSDL
LTSPDVGLLK
LASPELERLI
IQSSNGHITT
TPTPTQFLCP
KNVTDEQEGF
AEGFVRALAE
LHSQNTLPSV
TSAAQPVNGA
GMVAPAVASV
AGGSGSGGFS
ASLHSEPPVY
ANLSNFNPGA
LSSGGGAPSY
GAAGLAFPAQ
PQQQQQPPHH
LP
PurityGreater than 90.0% as determined by SDS-PAGE.
UsageNeoBiolab's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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