BLVRB Human-Reductase

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BLVRB Human

Qty


Total
$65
Catalog #
ENPS-394
Size
Description
BLVRB Human Recombinant amino produced in E.Coli is a single, non-glycosylated polypeptide chain containing 206 amino acids having a molecular mass of 22.1 kDa.The BLVRB is purified by proprietary chromatographic techniques.
Additional Information
IntroductionBLVRB (EC 1.3.1.24) catalyzes electron transfer from reduced pyridine nucleotides to flavins as well as methylene blue, pyrroloquinoline quinone, riboflavin, or methemoglobin. BLVRB is involved in protecting cells from oxidative damage or in regulating iron metabolism. BLVRB converts biliverdin to bilirubin in the liver, converting a double-bond between the second and third pyrrole ring into a single-bond. BLVRB plays a role as in human erythrocytic heme catabolic pathway and most mammalian species. Biliverdin reductase is abundantly expressed in kidney, spleen, liver and brain as well as at lower levels in the thymus and minimal levels being detected in testis.
SynonymsFLR, BVRB, SDR43U1, MGC117413, BLVRB, Flavin reductase, FR, NADPH-dependent diaphorase, NADPH-flavin reductase, Biliverdin reductase B, BVR-B, Biliverdin-IX beta-reductase, Green heme-binding protein, GHBP.
SourceEscherichia Coli.
Physical AppearanceSterile filtered colorless solution.
FormulationThe protein contains 20mM Tris-HCl buffer pH 8.5, 10% glycerol, and 1mM DTT.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMAVKKIAIFG
ATGQTGLTTL
AQAVQAGYEV
TVLVRDSSRL
PSEGPRPAHV
VVGDVLQAAD
VDKTVAGQDA
VIVLLGTRND
LSPTTVMSEG
ARNIVAAMKA
HGVDKVVACT
SAFLLWDPTK
VPPRLQAVTD
DHIRMHKVLR
ESGLKYVAVM
PPHIGDQPLT
GAYTVTLDGR
GPSRVISKHD
LGHFMLRCLT
TDEYDGHSTY
PSHQYQ.
PurityGreater than 95.0% as determined by SDS-PAGE.
UsageNeoBiolab's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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