ATF4 Human-Activating Transcription Factor

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ATF4 Human

Qty


Total
$65
Catalog #
PKPS-013
Size
Description
ATF4 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 510 amino acids (1-351 a.a.) and having a molecular mass of 56.6kDa.ATF4 is fused to a 159 amino acid His-Calmodulin-tag at N-terminus & purified by proprietary chromatographic techniques.
Additional Information
IntroductionActivating transcription factor 4 (ATF4) is a member of a family of DNA-binding proteins which includes the AP-1 family of transcription factors, cAMP-response element binding proteins and CREB-like proteins. The ATF4 gene encodes a transcription factor which was initially identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1.
SynonymsCyclic AMP-dependent transcription factor ATF-4, cAMP-dependent transcription factor, ATF-4, Activating transcription factor 4, Cyclic AMP-responsive element-binding protein 2, CREB-2, cAMP-responsive element-binding protein 2, DNA-binding protein, TAXREB
SourceEscherichia Coli.
Physical AppearanceATF3 is supplied as a sterile filtered clear solution.
FormulationATF4 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 1mM DTT and 10% glycerol.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMHHHHHHMAD
QLTEEQIAEF
KEAFSLFDKD
GDGTITTKEL
GTVMRSLGQN
PTEAELQDMI
NEVDADGNGT
IDFPEFLTMM
ARKMKDTDSE
EEIREAFRVF
DKDGNGYISA
AELRHVMTNL
GEKLTDEEVD
EMIREADIDG
DGQVNYEEFV
QMMTAKGSHM
TEMSFLSSEV
LVGDLMSPFD
QSGLGAEESL
GLLDDYLEVA
KHFKPHGFSS
DKAKAGSSEW
LAVDGLVSPS
NN
PurityGreater than 90.0% as determined by SDS-PAGE.
UsageNeoBiolab's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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