ACY1 Human-Other

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ACY1 Human

Qty


Total
$65
Catalog #
ENPS-303
Size
Description
ACY1 Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 428 amino acids (1-408 a.a.) and having a molecular mass of 48kDa. The ACY1 is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
Additional Information
IntroductionAminoacylase-1 is a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. ACY1 has been assigned to chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and ACY1 is the first member of a new family of zinc-binding enzymes.
SynonymsN-acyl-L-amino-acid amidohydrolase, ACY-1, ACY1D, ACYLASE, ACY1.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered clear solution.
FormulationThe ACY1 solution (0.5mg/ml) containing 20mM Tris-HCl pH-8, 1mM DTT & 10% glycerol.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MTSKGPEEEH
PSVTLFRQYL
RIRTVQPKPD
YGAAVAFFEE
TARQLGLGCQ
KVEVAPGYVV
TVLTWPGTNP
TLSSILLNSH
TDVVPVFKEH
WSHDPFEAFKDSEGYIYARG
AQDMKCVSIQ
YLEAVRRLKV
EGHRFPRTIH
MTFVPDEEVG
GHQGMELFVQ
RPEFHALRAG
FALDEGIANP
TDAFTVFYSE
RSPWWVRVTS
TGRPGHASRF
MED
PurityGreater than 90.0% as determined by SDS-PAGE.
UsageNeoBiolab's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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