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Our customer service representatives are available 24 hours, Monday through Friday to assist you.Reactivity | Human Rat |
Tested applications | WB IHC |
Recommended Dilution | WB 1:200 - 1:500 IHC 1:50 - 1:100 |
Calculated MW | 50kDa |
Observed MW | Refer to Figures |
Immunogen | Recombinant protein of human TNFRSF10A |
Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Concentration | bp |
Synonym | DR4; APO2; CD261; TRAILR1; TRAILR-1 |
Western blot analysis of extracts of various cells, using TNFRSF10A antibody.
Immunohistochemistry of paraffin-embedded human stomach using TNFRSF10A antibody at dilution of 1:100 (x40 lens).
Immunohistochemistry of paraffin-embedded human prostate using TNFRSF10A antibody at dilution of 1:100 (x40 lens).
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.
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