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Tested applications | WB |
Recommended Dilution | WB 1:200 - 1:2000 |
Calculated MW | 60kDa |
Observed MW | Refer to figures |
Immunogen | Recombinant protein of human THBD |
Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | TM; THRM; AHUS6; BDCA3; CD141; THPH12; |
The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia.
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