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Tested applications | WB IP |
Recommended Dilution | WB 1:500 - 1:2000 IP 1:20 - 1:100 |
Calculated MW | 79kDa |
Observed MW | Refer to figures |
Immunogen | Recombinant protein of human TBX3 |
Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Concentration | bk |
Synonym | UMS; XHL; TBX3-ISO; |
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms; however, the full length nature of one variant has not been determined.
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