Accelerate Biological Research
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Our customer service representatives are available 24 hours, Monday through Friday to assist you.| Reactivity | Human Mouse |
| Tested applications | WB |
| Recommended Dilution | WB 1:200 - 1:2000 |
| Calculated MW | 42kDa |
| Observed MW | Refer to figures |
| Immunogen | Recombinant protein of human SPOP |
| Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | TEF2; BTBD32; |
This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein.
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