Phospho-Src-Y527-Polyclonal Antibodies

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Phospho-Src-Y527

Qty


Total
$300
Catalog #
AP0470
Antibody Type
Polyclonal Antibody
Gene ID
6714
Swiss Prot
P12931
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman
Tested applicationsWB
Recommended DilutionWB 1:500 - 1:2000
Calculated MW60kDa
Observed MWRefer to Figures
ImmunogenA phospho specific peptide corresponding to residues surrounding Y527 of human Src
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentrationoqt
SynonymASV; SRC1; c-SRC; p60-Src;
Images
  • AP0470: image 1

    Western blot analysis of extracts of various cell lines, using Phospho-Src-Y527 antibody.

Background

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.

Protocol

N/A

MSDS
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