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Tested applications | WB IHC IF |
Recommended Dilution | WB 1:500 - 1:1000 IHC 1:50 - 1:100 IF 1:50 - 1:200 |
Calculated MW | 289kDa |
Observed MW | Refer to Figures |
Immunogen | A phospho specific peptide corresponding to residues surrounding S2448 of human MTOR |
Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Concentration | cfor |
Synonym | FRAP;FRAP1;FRAP2;RAFT1; |
The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene.
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