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Tested applications | WB |
Recommended Dilution | WB 1:500 - 1:2000 |
Observed MW | Refer to Figures |
Immunogen | A phospho specific peptide corresponding to residues surrounding Y1280 of human IGF1R |
Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Concentration | b |
Synonym | IGFR; CD221; IGFIR; JTK13; |
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival.
N/A