Phospho-HIST1H3B-T11-Monoclonal Antibodies

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Phospho-HIST1H3B-T11

Qty


Total
$300
Catalog #
AP0093
Antibody Type
Polyclonal Antibody
Gene ID
8350
Swiss Prot
P68431
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman Mouse Rat
Tested applicationsWB IF
Recommended DilutionWB 1:500 - 1:2000 IF 1:50 - 1:200
Observed MWRefer to Figures
ImmunogenA phospho specific peptide corresponding to residues surrounding T11 of human HIST1H3B
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentrationq
SynonymH3/A; H3FA
Images
  • AP0093: image 1

    Immunofluorescence analysis of U2OS cell using Phospho-HIST1H3B-T11 antibody. Blue: DAPI for nuclear staining.

Background

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.

Protocol

N/A

MSDS
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