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Our customer service representatives are available 24 hours, Monday through Friday to assist you.| Reactivity | Human Mouse Rat | 
| Tested applications | WB IHC | 
| Recommended Dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:200 | 
| Calculated MW | 81kDa | 
| Observed MW | Refer to figures | 
| Immunogen | Recombinant Protein of human LEPREL1 | 
| Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. | 
| Concentration | f | 
| Synonym | MCVD; MLAT4; LEPREL1; | 
This gene encodes a member of the prolyl 3-hydroxylase subfamily of 2-oxo-glutarate-dependent dioxygenases. These enzymes play a critical role in collagen chain assembly, stability and cross-linking by catalyzing post-translational 3-hydroxylation of proline residues. Mutations in this gene are associated with nonsyndromic severe myopia with cataract and vitreoretinal degeneration, and downregulation of this gene may play a role in breast cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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