EYA3-Polyclonal Antibodies

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EYA3

Qty


Total
$220
Catalog #
A7893
Antibody Type
Polyclonal Antibody
Gene ID
2140
Swiss Prot
Q99504
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman Mouse Rat
Tested applicationsWB IHC
Recommended DilutionWB 1:500 - 1:2000 IHC 1:50 - 1:200
Calculated MW63kDa
Observed MWRefer to figures
ImmunogenRecombinant protein of human EYA3
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Images
  • A7893: image 1

    Western blot analysis of extracts of various cells, using EYA3 antibody.

  • A7893: image 2

    Immunohistochemistry of paraffin-embedded rat kidney using EYA3 antibody at dilution of 1:100 (40x lens).

  • A7893: image 3

    Immunohistochemistry of paraffin-embedded human kidney using EYA3 antibody at dilution of 1:100 (40x lens).

  • A7893: image 4

    Immunohistochemistry of paraffin-embedded human gastric using EYA3 antibody at dilution of 1:100 (40x lens).

  • A7893: image 5

    Immunohistochemistry of paraffin-embedded mouse liver using EYA3 antibody at dilution of 1:100 (40x lens).

Background

This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator and have a role during development. It can act as a mediator of chemoresistance and cell survival in Ewing sarcoma cells, where this gene is up-regulated via a micro-RNA that binds to the 3' UTR of the transcript. A similar protein in mice acts as a transcriptional activator. Alternative splicing of this gene results in multiple transcript variants.

Protocol

N/A

MSDS
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