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Tested applications | WB |
Recommended Dilution | WB 1:500 - 1:2000 |
Calculated MW | 104kDa |
Observed MW | Refer to figures |
Immunogen | Recombinant protein of human ERCC4 |
Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | XPF; RAD1; FANCQ; ERCC11; |
The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6).
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