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Our customer service representatives are available 24 hours, Monday through Friday to assist you.| Reactivity | Human Mouse Rat |
| Tested applications | WB IF |
| Recommended Dilution | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
| Calculated MW | 19kDa |
| Observed MW | Refer to figures |
| Immunogen | Recombinant protein of human CFL2 |
| Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | NEM7; |
This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants.
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